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A BAC contig of approximately 400 kb contains the classical class I major histocompatibility complex (MHC) genes of cattle.

Eur. J. Immunogenet.2002 Feb;29(1):65-8
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摘要


A cattle BAC library derived from an MHC homozygous animal was screened for MHC class I genes. This revealed at least nine class I-related genes in a contig spanning approximately 400 kb, and several additional genes on other clones. The three classical class I genes expressed on this haplotype (A14) were shown to be distributed over a region at most 212 kb apart.

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基因功能


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