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The sibling species Drosophila melanogaster and Drosophila simulans differ in the expression profile of glutathione S-transferases.

Comp. Biochem. Physiol. B, Biochem. Mol. Biol.2001 Jul;129(4):837-41
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摘要

Two major forms of glutathione S-transferase are known in Drosophila melanogaster: GST D and GST 2. In the present paper we report the existence of a third major form of glutathione S-transferase in Drosophila simulans. Induction with phenobarbital revealed a different regulation of GST between these species. Despite the fact that these two species are closely related, there was a difference in the expression profile of the enzyme implicated in the detoxification system, suggesting variations in capacity to suit their environment.

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