The L6 membrane proteins--a new four-transmembrane superfamily.

Protein Sci.2000 Aug;9(8):1594-600. doi:10.1110/ps.9.8.1594

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L6, IL-TMP, and TM4SF5 are cell surface proteins predicted to have four transmembrane domains. Previous sequence analysis led to their assignment as members of the tetraspanin superfamily. In this paper, we identify a new sequence (L6D) that is strikingly similar to L6, IL-TMP, and TM4SF5. Analyses of these four sequences indicate that they are not significantly related to genuine tetraspanins, but instead constitute their own L6 superfamily.

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The L6 membrane proteins--a new four-transmembrane superfamily.

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