Genetic dissection of gustatory sensitivity to bitterness (sucrose octaacetate) in mice.
C. R. Acad. Sci. III, Sci. Vie. 1999 Oct;322(10):831-6
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摘要
Genes implicated in consumption of a bitter compound, sucrose octaacetate (SOA), were investigated using a full genomic scanning strategy. For a 0.1 mM concentration, two QTL reached 5.8 and 6.5 lod scores on chromosomes 2 (77 cM) and 11 (14 cM), respectively. For a 1 mM concentration, the Soa linkage on chromosome 6 (58 cM, lod score 9.4) was replicated, and another QTL was found on chromosome 19 (15 cM, lod score 3.2). Candidacy of previously identified genes in the close vicinity of the peak of the QTL was examined.
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基因功能
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原始数据
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文献解读
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